I have found twisting to help wires that sound a little congested, especially mid bass down. Subtler up higher, it will heighten the sense of detail and micro dynamics articulation across the spectrum. But for me, when I like it, it is the bottom that points me to doing it.
I don't think this is my room, because I find the same effect in both my listening spaces. That most cable makers do it is indicative of something they at least theorize on, but in my experience, also hear...the good makers being into better sound supported by theory rather than the opposite.
That said, it depends in my experience. If everything else together with the wires is right without twists, then it is good. I think I tended to like the styx better untwisted too. And since these WE wires are pretty thin relatively speaking (likely to have less heavy/congested bass tendency), and have a shield (dealing with RF and EMF), they may not be inclined to low end congestion or interference distortions.
EDIT: Oops...looks like the WE wire does not have a shield. It will be interesting if twisting sounds better or worse. Being so little, the sense of warmth/musicality may be may be better untwisted.
A good test is a light duty twist about a foot apart, not imbedding it in the wire shape, but indicative of the effect to expect with more twists. The last pair I chose to twist was a rich and warm wire with gold and silver particles in oil surrounding pure copper. I ended up with maybe 2-3 inch twists on them and it really helped solve "smearing," to me, making a nice cable really nice. Good to my tastes for that wire.