Dave,
I'm using the Tung Sol 7581As now and I'm biasing at 64mA. I tend to bias towards the high side of tubes but try to stay below 70mA for heat reasons. I think if you bias high you will shorten tube life some. I got my 7851As for less than $100/quad so I'm not too worried if they go a little sooner.
Here is a bias calculator that I've used:
https://www.tedweber.com/webervst/tubes1/calcbias.htmYou may have to use a similar class tube since all aren't on the list. I seem to remember Jeff measuring his ZMA plate voltage somewhere in the 480V range. If you search his old posts you might find it.
Let us know how you like the 7581As as compared with the KT66s, My favorite are the 7027As followed closely by the 7581As.